The show has to do adapt to Hayden Panettiere’s medical leave. What can you say specifically about what kind of adjustments the show will be making to accommodate that? What made you confident that the show could continue without one of it’s lead stars for several episodes?
Showrunner Dee Johnson: The show has had to jump through some hoops, but we’ve done it before and it probably won’t be the last time. Real life is always a factor in planning a full network season order. Hayden is a huge player for us and she may be out for a bit but fortunately, we are blessed with a terrific ensemble cast.
Source and more: THR